Dr Mehreen Datoo
Dr Mehreen Datoo is an Associate Fellow of Green Templeton College and a Clinical Lecturer in Infectious Diseases, Nuffield Department of Medicine, University of Oxford.
Mehreen is an experienced Clinical Research Fellow with a demonstrated history of working in pioneering vaccine research at the Jenner Institute, University of Oxford. She has been central to the Oxford R21/Matrix-M™ malaria vaccine team that received WHO recommendation for use in 2023, paving the way for global roll-out.
Mehreen completed her medical degree at King’s College London and spent time at the London School of Hygiene and Tropical Medicine before coming to Oxford in 2016 for her clinical training. She achieved her DPhil on the clinical development of an anti-sporozoite malaria vaccine and as part of this work she explored the correlation between malaria vaccine immune responses and the gut microbiome. Mehreen is now working on new vaccine candidates to target other malaria parasites whilst also undertaking her Infectious Diseases and Microbiology training.
Aside from her expertise in malaria vaccine trials, Mehreen has worked on ebola vaccine trials, and during the pandemic, Mehreen was a clinical research doctor on the Oxford COVID-19 vaccine trials while also working at the John Radcliffe Hospital as a medical registrar.
Mehreen has worked as a medical doctor and carried out clinical research across a number of countries including Burkina Faso, Kenya, Tanzania, United Kingdom and Zambia..
To read more about Mehreen’s work, please see some of her key papers:
- ‘Efficacy of a low-dose candidate malaria vaccine, R21 in adjuvant Matrix-M, with seasonal administration to children in Burkina Faso: a randomised controlled trial’, The Lancet
- ‘Efficacy and immunogenicity of R21/Matrix-M vaccine against clinical malaria after 2 years’ follow-up in children in Burkina Faso: a phase 1/2b randomised controlled trial’, The Lancet
- ‘A Phase III Randomised Controlled Trial Evaluating the Malaria Vaccine Candidate R21/Matrix-M™ in African Children’, Preprints with The Lancet
Contact: mehreen.datoo@ndm.ox.ac.uk
